Meister D, Fürst A, Kaegi B, Struchen C, Kaser-Hotz B, Flückiger M
Veterinärchirurgischen Klinik der Universität Zürich.
Tierarztl Prax. 1993 Oct;21(5):437-43.
In a retrospective study the tolerance to Teflon coated catheters in long-term intravenous medication was evaluated in 80 horses. Catheters were inserted into the jugular vein and remained there for 3 to 30 days (average 8.6 days). Catheters were flushed using an heparinized solution after each medication administration. The site of catheter placement was evaluated daily for swelling, pain and venous distensibility respectively. Swelling at the site of insertion was noted in 10 horses, a small subcutaneous abscess formation was identified in one horse. Fourteen sonographic evaluations were performed on 10 horses, demonstrating perivascular changes in four. Thrombus formation did not occur. In all horses the catheter could be identified floating freely within the vascular lumen. Catheter failure occurred in nearly a third of all cases either as a result of mechanical failure or of pull-out by the horse. After removal of the catheter no adverse side effects attributable to the mode of medication were noted in any of the horses. In conclusion, intravenous medication using Teflon-coated catheters is a suitable alternative to other modes of administration.
在一项回顾性研究中,对80匹马使用涂有特氟龙的导管进行长期静脉给药的耐受性进行了评估。将导管插入颈静脉,并在那里留置3至30天(平均8.6天)。每次给药后,使用肝素化溶液冲洗导管。每天分别对导管置入部位进行肿胀、疼痛和静脉扩张性评估。10匹马在插入部位出现肿胀,1匹马出现小的皮下脓肿形成。对10匹马进行了14次超声评估,其中4匹马显示血管周围有变化。未发生血栓形成。在所有马匹中,均可看到导管在血管腔内自由漂浮。近三分之一的病例出现导管故障,原因要么是机械故障,要么是被马拔出。拔除导管后,未在任何一匹马身上发现因给药方式导致的不良副作用。总之,使用涂有特氟龙的导管进行静脉给药是其他给药方式的合适替代方法。