Takeda M, Katayama Y, Takahashi H, Saito K, Tsutsui T, Komeyama T
Department of Urology, Niigata University School of Medicine, Japan.
Urol Int. 1993;51(3):177-80. doi: 10.1159/000282539.
A 46-year-old housewife with regurgitation of mitral valve developed acute renal failure due to acute thrombosis of bilateral renal arteries after cardiac catheterization. A regional fibrinolytic therapy using transarterial infusion of tissue plasminogen activator (t-PA) was performed at 8 h after the onset, and was successful. She could be taken off hemodialysis 2 weeks after the fibrinolytic therapy, and could be successfully operated on with mitral valve replacement 7 months after that. Three years after mitral valve replacement, her serum creatinine was 148 mumol/l. This is the longest follow-up case after regional transarterial fibrinolysis of acute thrombosis of renal artery using t-PA, and this therapy is a safe and good one for acute thrombosis of renal artery.
一名46岁患有二尖瓣反流的家庭主妇在心脏导管插入术后因双侧肾动脉急性血栓形成而发生急性肾衰竭。在发病8小时后进行了经动脉输注组织型纤溶酶原激活剂（t-PA）的局部纤维蛋白溶解疗法，治疗成功。纤维蛋白溶解疗法2周后她可以停止血液透析，之后7个月成功进行了二尖瓣置换手术。二尖瓣置换术后三年，她的血清肌酐为148μmol/l。这是使用t-PA对肾动脉急性血栓形成进行局部经动脉纤维蛋白溶解术后随访时间最长的病例，该疗法对肾动脉急性血栓形成是一种安全且良好的治疗方法。
