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十二指肠胃反流患者幽门螺杆菌感染的发生率

[Incidence of Helicobacter pylori infections in patients with duodenogastric reflux].

作者信息

Poniewierka E, Gościniak G, Matysiak-Budnik T

机构信息

Katedry i Kliniki Gastroenterologii Ak. Med. im. Piastów Slaskich, Wrocławiu.

出版信息

Wiad Lek. 1993 Apr;46(7-8):271-3.

PMID:8249413
Abstract

The purpose of the work was a comparison of the incidence of Helicobacter pylori (HP) infections in persons with dyspeptic symptoms of non-ulcer dyspepsia (NUD) character in relation to the presence or absence of duodenogastric reflux (DGR). The study included 80 patients aged from 17 to 80 years, 21 males and 59 females. In all studied patients endoscopy of upper digestive tract segment was performed with biopsy specimen taking for microbiological investigations. From each patient two biopsy specimens were taken from the prepyloric part and the fundus. The specimens were subjected to a microbiological analysis using the rapid urease test, culturing, and direct preparation. The presence of duodenogastric reflux was evaluated during endoscopy. In persons with diagnosed NUD and duodenogastric reflux, lower incidence of HP infections was found than in patients with the same diagnosis but without the reflux.

摘要

这项工作的目的是比较具有非溃疡性消化不良(NUD)特征的消化不良症状患者中幽门螺杆菌(HP)感染的发生率与十二指肠胃反流(DGR)的有无之间的关系。该研究纳入了80名年龄在17至80岁之间的患者,其中男性21名,女性59名。对所有研究患者均进行了上消化道内镜检查,并取活检标本进行微生物学检查。从每位患者的幽门前部和胃底各取两份活检标本。标本采用快速尿素酶试验、培养和直接制片进行微生物学分析。在内镜检查期间评估十二指肠胃反流的存在情况。在诊断为NUD且有十二指肠胃反流的患者中,发现HP感染的发生率低于诊断相同但无反流的患者。

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