Hopper K D, Abendroth C S, Sturtz K W, Matthews Y L, Shirk S J, Stevens L A
Department of Radiology, Penn State University, Hershey 17033.
AJR Am J Roentgenol. 1993 Dec;161(6):1293-7. doi: 10.2214/ajr.161.6.8249745.
The purpose of this study was to compare several of the commonly used needles with several of the new automated biopsy devices (biopsy guns) for biopsy of diffuse hepatic disease.
Nine different biopsy needles or automated devices were each used to do three biopsies of 10 cadaveric livers. The specimens were reviewed in a blinded fashion by a pathologist who did not know which needle or device was used, and they were compared on the basis of a previously published histopathologic grading scale.
The three conventional biopsy needles (16-gauge Jamshidi, 18-gauge Sure-Cut, and 14-gauge Tru-Cut) obtained a large amount of tissue with an average of 4.1 intact portal triads per biopsy. The 18-gauge Biopty gun obtained equivalent results. The 18-gauge Autovac gun with a 2-cm biopsy depth did not obtain any tissue in 18.5% of attempts. The 14- and 16-gauge Biopty guns and the 18-gauge Autovac gun with a 4-cm biopsy depth performed best with respect to fragment size and number of intact portal triads.
Automated biopsy devices can provide more diagnostic specimens than can manual or conventional needles in biopsy for diffuse hepatic disease.
本研究旨在比较几种常用活检针与几种新型自动活检装置（活检枪）在弥漫性肝脏疾病活检中的应用情况。
使用9种不同的活检针或自动活检装置，分别对10个尸体肝脏进行3次活检。由一位不知所用活检针或装置的病理学家以盲法对标本进行评估，并根据先前公布的组织病理学分级标准进行比较。
三种传统活检针（16号Jamshidi针、18号Sure-Cut针和14号Tru-Cut针）获取的组织量较大，每次活检平均有4.1个完整的门三联。18号Biopty枪取得了类似的结果。活检深度为2厘米的18号Autovac枪在18.5%的尝试中未获取到任何组织。活检深度为4厘米的14号和16号Biopty枪以及18号Autovac枪在碎片大小和完整门三联数量方面表现最佳。
在弥漫性肝脏疾病活检中，自动活检装置比手动或传统活检针能提供更多的诊断标本。
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