Skues M A, Welchew E A
Department of Anaesthesia, Northern General Hospital, Sheffield.
Anaesthesia. 1993 Nov;48(11):989-97. doi: 10.1111/j.1365-2044.1993.tb07482.x.
A review of the implications of rheumatoid arthritis on peri-operative anaesthetic management is presented. Pre-operative assessment should include a careful search for articular and systemic manifestations of the disease that may complicate intraoperative care. Drug disposition may vary from the normal patient as a result of changes in serum protein binding, together with possible exaggeration of pharmacodynamic responses. Airway management presents one of the greatest challenges to the anaesthetist, and care in manipulation of the cervical spine is paramount.
本文综述了类风湿性关节炎对围手术期麻醉管理的影响。术前评估应仔细查找可能使术中护理复杂化的该疾病的关节和全身表现。由于血清蛋白结合的变化以及药效学反应可能被夸大，药物处置情况可能与正常患者不同。气道管理是麻醉医生面临的最大挑战之一，颈椎操作时的护理至关重要。
