Jorge S do C
Hospital e Maternidade Brasil-Santo André-SP.
Arq Bras Cardiol. 1993 Mar;60(3):177-82.
From 1985 to 1990, 120 patients within 6h after the onset of acute myocardial infarction were submitted to thrombolytic treatment. In 4 patients, there were clinical and electrocardiographic (ECG) changes of reinfarction. Three of them were undergone to a second thrombolytic therapy with streptokinase (SK). Two had infarction of the inferior wall, and one on the anterior wall. The patients were managed with the same SK dosage as in the first episode and the same protocol of infusion. All 3 patients, after new SK infusion showed evidence of myocardial reperfusion with relief of pain and improvement of the ECG. One patient, 24h after retreatment, had another reinfarction treated with emergency angioplasty of the right coronary artery, which was totally occluded. One patient (case n. 2), presented haematoma of right arm after punction of the subclavian vein and the other two patients did not show any serious intecorrence related to the new thrombolytic treatment. All of them were found alive over one year of follow-up.
1985年至1990年，120例急性心肌梗死发病6小时内的患者接受了溶栓治疗。4例出现了再梗死的临床和心电图（ECG）变化。其中3例接受了链激酶（SK）第二次溶栓治疗。2例为下壁梗死，1例为前壁梗死。患者接受与首次相同剂量的SK及相同的输注方案治疗。所有3例患者在新的SK输注后均显示出心肌再灌注的迹象，疼痛缓解且心电图改善。1例患者在再次治疗24小时后再次发生再梗死，接受了完全闭塞的右冠状动脉紧急血管成形术治疗。1例患者（病例编号2）在锁骨下静脉穿刺后出现右臂血肿，另外2例患者未出现与新的溶栓治疗相关的任何严重并发症。随访一年以上发现他们均存活。
