Krishnamurti A, Sanides F, Welker W I
Brain Behav Evol. 1976;13(4):267-83. doi: 10.1159/000123815.
Microelectrode mapping methods and strategies were developed to map fine details of the somatotopic organization of somatic sensory cortex (SI) in slow loris. In-depth, multiple-unit recording, and threshold natural stimulation of skin and hari revealed three modality-specific cortical areas. The centrally located one was activated by extremely light touch and the somatopic organization of peripheral projections to it was mapped in detail. As many as 25 punctures/mm2 were made in delineating these details. The microelectrode mapping method used revealed smaller receptive fields, lesser degrees of overlap, a more differentiated pattern of peripheral projections, and a more precise correlation of electrophysiological results with underlying cytoarchitectonic details than did the usual macroelectrode surface recording method. These results and the correlations found between different physiologically defined areas and cortical sulci are discussed as they pertain to methodological advances in studies of cerebral localization of function.
开发了微电极测绘方法和策略，以绘制懒猴躯体感觉皮层（SI）躯体定位组织的精细细节。深入的多单位记录以及对皮肤和毛发的阈下自然刺激揭示了三个模态特异性皮层区域。位于中央的那个区域由极轻的触摸激活，并详细绘制了其外周投射的躯体定位组织。在描绘这些细节时，每平方毫米进行了多达25次穿刺。与通常的宏观电极表面记录方法相比，所使用的微电极测绘方法揭示了更小的感受野、更小的重叠程度、更分化的外周投射模式，以及电生理结果与潜在细胞结构细节更精确的相关性。讨论了这些结果以及在不同生理定义区域和脑沟之间发现的相关性，因为它们与功能脑定位研究的方法学进展有关。
