Surana R, Moloney R, Fitzgerald R J
Children's Hospital, Dublin, Republic of Ireland.
Surg Oncol. 1993;2(2):133-6. doi: 10.1016/0960-7404(93)90023-r.
Heterotopic salivary tumours in the upper neck are rare. Three children, one with mucoepidermoid carcinoma and two with pleomorphic adenoma in ectopic cervical sites are presented. Local complete excision was successful in the patients with pleomorphic adenoma. More extensive surgery was undertaken for the mucoepidermoid carcinoma. All three patients remain disease free at 3-6 years follow-up. Oncogenesis of heterotopic salivary tissue entrapped in an upper cervical lymph node during embryogenesis is a possible etiological mechanism. In a patient with a cervical malignant salivary tumour, a careful search should be made to find a primary tumour. In the event of a negative search, this should be considered the primary tumour and treated appropriately.
上颈部异位唾液腺肿瘤较为罕见。本文报告了3例儿童病例,其中1例为黏液表皮样癌,2例为异位颈部的多形性腺瘤。多形性腺瘤患者通过局部完整切除获得成功。对黏液表皮样癌则采取了更广泛的手术。所有3例患者在3至6年的随访中均无疾病复发。胚胎发育期间被困在上颈部淋巴结中的异位唾液腺组织发生肿瘤形成是一种可能的病因机制。对于患有颈部恶性唾液腺肿瘤的患者,应仔细寻找原发肿瘤。如果未找到原发肿瘤,则应将此视为原发肿瘤并进行适当治疗。