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[几种血吸虫-大鼠感染中免疫反应的变化]

[Variations in the immune response in several schistosome-rat infections].

作者信息

Leger N, Niel G, Notteghem M J, Forget E

出版信息

C R Acad Hebd Seances Acad Sci D. 1976 Jul 12;283(2):187-90.

PMID:825253
Abstract

The evolution of immunological reactions in two Rat strains, namely Rattus rattus from Guadeloupe and Rattus norvegicus var. albinos, was studied. Both have beem experimentally infested by three different strains of Schistosoma mansoni. We observed that Rattus rattus infested by the American strains reacts poorly and shows a persistant infection contrary to the results obtained with other infestations. So it appears that a special pathogenic complex might be present in Guadeloupe which could explain the role played by this rodent in the bilharziosis endemy.

摘要

研究了两种大鼠品系免疫反应的演变,即来自瓜德罗普岛的黑家鼠和白化挪威大鼠变种。二者均通过三种不同的曼氏血吸虫菌株进行实验性感染。我们观察到,被美国菌株感染的黑家鼠反应较差,并呈现持续性感染,这与其他感染所获得的结果相反。因此,似乎瓜德罗普岛可能存在一种特殊的致病复合体,这可以解释这种啮齿动物在血吸虫病流行中所起的作用。

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