McDonagh A J, Gawkrodger D J, Walker A E
Department of Dermatology, Royal Hallamshire Hospital, Sheffield, UK.
Clin Exp Dermatol. 1993 Nov;18(6):523-5. doi: 10.1111/j.1365-2230.1993.tb01021.x.
A recent outbreak of chloracne in 17 workers is reported at a plant manufacturing dichloroaniline derivatives. Comedones developed 6-12 weeks after accidental exposure to the chloracnegenic contaminants and were present in every case. Cutaneous xerosis and a folliculitis, previously only rarely described as manifestations of chloracne, were noted in half the patients. The pathogenesis of these lesions is uncertain but may involve a disorder of keratinization.
据报道，一家生产二氯苯胺衍生物的工厂有17名工人近期爆发了氯痤疮。在意外接触致氯痤疮污染物6至12周后出现了粉刺，且所有病例均有粉刺。半数患者出现了皮肤干燥和毛囊炎，此前仅有很少关于它们作为氯痤疮表现的描述。这些损害的发病机制尚不清楚，但可能涉及角化异常。
