Rogers N K, Bowen D I, Noble B A
Department of Ophthalmology, Harrogate District Hospital, UK.
Eye (Lond). 1993;7 ( Pt 4):594-6. doi: 10.1038/eye.1993.129.
The presence of fine epithelial deposits in a whorled pattern (cornea verticillata) as a consequence of treatment with amiodarone is well documented. We present a case of amiodarone keratopathy in a grafted cornea which is atypical in that the orientation of the pattern is rotated through nearly 90 degrees to that normally observed. This observation runs counter to the hypothesis that cornea verticillata is a manifestation of the line of lid closure. We speculate on the mechanism directing the migrational pathways of epithelial cells.
胺碘酮治疗导致呈螺旋状分布的细微上皮沉积物（涡状角膜病变）的存在已有充分记录。我们报告了一例移植角膜中胺碘酮角膜病变的病例，该病例的非典型之处在于，沉积物图案的方向相对于正常观察到的情况旋转了近90度。这一观察结果与涡状角膜病变是睑裂闭合线表现的假说相悖。我们推测了指导上皮细胞迁移途径的机制。
