Nishiura N, Miyazaki T
Folia Psychiatr Neurol Jpn. 1976;30(3):253-61. doi: 10.1111/j.1440-1819.1976.tb02262.x.
Childhood epilepsy with nocturnal seizure and rolandic (centro-temporal) discharge on EEG, had recently been noted by some French and other European authors. These types of epilepsy usually appeared in middle childhood and showed a favorable effect ot anticonvulsant therapy. The present investigation deals with analysis of seizures and of some characteristics of rolandic discharge, particularly with respect to the cerebral maturational process involved in the appearance of seizure discharge. The patients were selected out by the symptoms of epilepsy and features of EEG's, consisting of 20 children in total. Fifteen patients showed somatomotor attacks and five showed somatosensory as well as somatomotor attacks. As for the duration of seizure, those who had seizures before three and 10 years of age, had attacks for relatively short periods, whereas those who had attacks from four to nine years of age, usually had longer duration. The amplitude of "RD" remained lower than 50 muv up to three years of age, whereas it reached as high as 200 muv up to nine years, particularly during sleep, which became lower after the age of 10. It was concluded that there is an age dependency between the ages of four and nine.
近期一些法国及其他欧洲作者注意到了一种儿童癫痫,其伴有夜间发作且脑电图显示有中央颞区(罗兰区)放电。这类癫痫通常出现在童年中期,对抗惊厥治疗效果良好。本研究旨在分析发作情况及罗兰区放电的一些特征,特别是关于发作放电出现所涉及的脑成熟过程。患者通过癫痫症状和脑电图特征进行筛选,共20名儿童。15名患者表现为躯体运动性发作,5名患者表现为躯体感觉性及躯体运动性发作。至于发作持续时间,3岁及10岁前发作的患者,发作时间相对较短,而4至9岁发作的患者,发作持续时间通常较长。“RD”(罗兰区放电)的波幅在3岁前一直低于50微伏,而到9岁时高达200微伏,尤其是在睡眠期间,10岁后波幅降低。研究得出结论,在4至9岁之间存在年龄相关性。