Ebina H, Funato T, Kawamura T, Ishimori A, Satoh K, Terasaki S, Chiba M, Yanagiya T
Division of Clinical and Laboratory Medicine, Tohoku University School of Medicine, Sendai.
Rinsho Byori. 1993 Sep;41(9):1049-53.
Recently the risk of ischemic heart disease (IHD) is increasing in young generations. Thus, we evaluated the degree of hyperlipidemia in the students of high school in Miyagi prefecture. At first, we examined the plasma level of total cholesterol in all students as screening. About 10% of all the students showed high level of total cholesterol over 200mg/dl. For second screening, we examined further indexes for hyperlipidemia including lipids, glucose and blood pressure at fasting state and got information about family history, diet and exercise. There was positive correlation between total cholesterol and LDL-cholesterol (LDL-C), but no relation was found among others. Lipoprotein (a) which was an independent factor of IHD showed a broad distribution as described before, and had no relation with other lipid levels. Early education and a familial consultation for protecting from IHD should be followed after the screening of lipids levels.
近年来,年轻一代患缺血性心脏病(IHD)的风险在增加。因此,我们评估了宫城县高中生的高脂血症程度。首先,我们检测了所有学生的血浆总胆固醇水平作为筛查。所有学生中约10%的人总胆固醇水平高于200mg/dl。作为第二次筛查,我们检测了空腹状态下包括血脂、血糖和血压在内的高脂血症进一步指标,并获取了家族史、饮食和运动方面的信息。总胆固醇与低密度脂蛋白胆固醇(LDL-C)之间存在正相关,但其他指标之间未发现关联。脂蛋白(a)作为IHD的一个独立因素,如前所述呈现广泛分布,且与其他血脂水平无关。在血脂水平筛查后,应进行早期教育和家庭咨询以预防IHD。