争分夺秒：NTP酶维持生物保真度的范例。
Beat the clock: paradigms for NTPases in the maintenance of biological fidelity.
作者信息
Burgess S M, Guthrie C
机构信息
Department of Biochemistry and Molecular Biology, Harvard University, Cambridge, MA 02138.
出版信息
Trends Biochem Sci. 1993 Oct;18(10):381-4. doi: 10.1016/0968-0004(93)90094-4.
PMID:8256287
Abstract
Kinetic proofreading is a strategy used by cells to reduce the number of errors made when replicating and expressing genetic information. Recent advances in mRNA splicing suggest a variation on the theme of previously described kinetic proofreading mechanisms, which may apply to other multicomponent assembly processes in the cell.
摘要
动力学校对是细胞用于减少复制和表达遗传信息时所产生错误数量的一种策略。mRNA剪接方面的最新进展表明，此前描述的动力学校对机制存在一种变体，这可能适用于细胞中的其他多组分组装过程。
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