甲泼尼龙治疗持续性异常肌肉活动综合征1例的疗效
Efficacy of methylprednisolone administration in a case of continuous abnormal muscle activity syndrome.
作者信息
Jalil P, Frenkel C, Guiloff R, Gajewski C, Vergara F
机构信息
Servicio de Neurologia, Hospital Dr. Sotero del Rio, Chile.
出版信息
Acta Neurol Scand. 1993 Sep;88(3):234-5. doi: 10.1111/j.1600-0404.1993.tb04225.x.
Abstract
We report a 20-year-old woman with continuous abnormal muscle activity syndrome in which pharmacological blockade of different sites of the motor unit demonstrates a peripheral nerve origin for the abnormal muscle activity. The case showed no markers of autoimmune disease. A rapid recovery after high dose i.v. methylprednisolone was observed supporting the hypothesis of an autoimmune pathogenesis.
摘要
我们报告了一名20岁患有持续性异常肌肉活动综合征的女性，其中对运动单位不同部位的药理学阻断证明了异常肌肉活动的周围神经起源。该病例未显示自身免疫性疾病的标志物。观察到高剂量静脉注射甲泼尼龙后迅速恢复，支持自身免疫发病机制的假说。
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