Johnston M E, Langton K B, Haynes R B, Mathieu A
McMaster University, Hamilton, Ontario, Canada.
Ann Intern Med. 1994 Jan 15;120(2):135-42. doi: 10.7326/0003-4819-120-2-199401150-00007.
To review the evidence from controlled trials of the effects of computer-based clinical decision support systems (CDSSs) on clinician performance and patient outcomes.
The literature in the MEDLARS, EMBASE, SCISEARCH, and INSPEC databases was searched from 1974 to the present. Conference proceedings and reference lists of relevant articles were reviewed. Evaluators of CDSSs were asked to identify additional studies.
793 citations were examined, and 28 controlled trials that met predefined criteria were reviewed in detail.
Study quality was assessed, and data on setting, clinicians and patients, method of allocation, computer system, and outcomes were abstracted and verified using a structured form. Separate summaries were prepared for physician and patient outcomes. Within each of these categories, studies were classified further according to the primary purpose of the CDSS: drug dose determination, diagnosis, or quality assurance.
Three of 4 studies of computer-assisted dosing, 1 of 5 studies of computer-aided diagnosis, 4 of 6 studies of preventive care reminder systems, and 7 of 9 studies of computer-aided quality assurance for active medical care that assessed clinician performance showed improvements in clinician performance using a CDSS. Three of 10 studies that assessed patient outcomes reported significant improvements.
Strong evidence suggests that some CDSSs can improve physician performance. Additional well-designed studies are needed to assess their effects and cost-effectiveness, especially on patient outcomes.
回顾基于计算机的临床决策支持系统(CDSS)对临床医生表现及患者预后影响的对照试验证据。
检索了MEDLARS、EMBASE、SCISEARCH和INSPEC数据库1974年至今的文献。查阅了会议论文集及相关文章的参考文献列表。CDSS评估者被要求找出其他研究。
检查了793篇文献,详细回顾了28项符合预定义标准的对照试验。
评估研究质量,使用结构化表格提取并核实关于研究背景、临床医生和患者、分配方法、计算机系统及预后的数据。分别针对医生和患者的预后编写总结。在每个类别中,根据CDSS的主要目的对研究进一步分类:药物剂量确定、诊断或质量保证。
评估临床医生表现的4项计算机辅助给药研究中有3项、5项计算机辅助诊断研究中有1项、6项预防保健提醒系统研究中有4项、9项主动医疗的计算机辅助质量保证研究中有7项显示使用CDSS可改善临床医生表现。评估患者预后的10项研究中有3项报告有显著改善。
有力证据表明一些CDSS可改善医生表现。需要更多设计良好的研究来评估其效果和成本效益,尤其是对患者预后的影响。