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钝性创伤性肝损伤伴早期梭菌感染

Blunt traumatic liver injury associated with clostridial infection of early onset.

作者信息

Hemming A W, Scudamore C H, McGregor G I, Owen D

机构信息

Department of Surgery, University of British Columbia, Vancouver General Hospital.

出版信息

Can J Surg. 1993 Dec;36(6):529-32.

PMID:8258133
Abstract

Hepatic clostridial infections associated with blunt abdominal trauma are rare. Generally they occur from 2 weeks to 3 months after injury and are thought to result from the growth of normal enteric organisms, which are carried to the liver by the portal venous system and infect devitalized tissue. The authors describe two patients in whom the hepatic infection became established in less than 24 hours after injury and was due to Clostridium spp. The patients were successfully treated by hepatic resection and combination antimicrobial therapy. Hyperbaric oxygen was used as an adjunct in one case.

摘要

与钝性腹部创伤相关的肝梭菌感染较为罕见。一般在受伤后2周 至3个月发生,被认为是由正常肠道菌群生长所致,这些菌群通过门静脉系统进入肝脏并感染失活组织。作者描述了两名患者,其肝感染在受伤后不到24小时就已形成,病因是梭菌属。两名患者均通过肝切除和联合抗菌治疗成功治愈。其中1例使用了高压氧作为辅助治疗。

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