Rogers K
Postgrad Med J. 1976;52(5 Suppl):27-9.
Amethod of producing antithymocyte globulin is outlined. The in vitro and in vivo activities of the preparation were assessed. Two methods were used to obtain soluble antigen from freeze dried thymocyte membrane preparations. Atigens obtained from platelets were also tested. The experiments suggest that antigens evoking antilymphocyte globulin which give a high rosette inhibition titre can be partially separated from those evoking cytotoxic antibody. It is also possible that the antigens capable of evoking rosette inhibiting antibodies are not entirely confined to the lymphocyte population.
概述了一种生产抗胸腺细胞球蛋白的方法。评估了该制剂的体外和体内活性。使用两种方法从冻干的胸腺细胞膜制剂中获得可溶性抗原。还测试了从血小板中获得的抗原。实验表明，能引起高玫瑰花结抑制效价的抗淋巴细胞球蛋白的抗原可以与引起细胞毒性抗体的抗原部分分离。也有可能能够引起玫瑰花结抑制抗体的抗原并不完全局限于淋巴细胞群体。
