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在接受或未接受去铁胺治疗的重型和中间型β地中海贫血患者中,眼部受累情况与年龄相关。

Ocular involvement correlated with age in patients affected by major and intermedia beta-thalassemia treated or not with desferrioxamine.

作者信息

Rinaldi M, Della Corte M, Ruocco V, D'Onofrio C, Zanotta G, Romano A

机构信息

Eye Clinic First School of Medicine, University of Naples, Italy.

出版信息

Metab Pediatr Syst Ophthalmol (1985). 1993;16(1-2):23-5.

PMID:8259071
Abstract

We examined 25 patients affected from Cooley's disease and five by beta-thalassemia intermedia. The mean age was 15 +/- 6.3 years. Fifteen patients, (18 years or older) three of them affected by beta-thalassemia intermedia, presented ocular abnormalities. So it was impossible to establish a correlation between laboratory data and ocular damages; their observation, with reference to untreated beta-thalassemia subjects, suggested that ocular abnormalities cannot be only attributed to desferrioxamine treatment.

摘要

我们检查了25例患有库利氏病的患者和5例中间型β地中海贫血患者。平均年龄为15±6.3岁。15名患者(18岁及以上),其中3名患有中间型β地中海贫血,出现了眼部异常。因此,无法在实验室数据和眼部损害之间建立关联;对未经治疗的β地中海贫血患者的观察表明,眼部异常不能仅归因于去铁胺治疗。

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