Bluestein E C, Stewart W C
Department of Ophthalmology, Medical University of South Carolina, Charleston 29425-2236.
Ophthalmic Surg. 1993 Oct;24(10):669-73.
We compared the results achieved in 22 consecutive patients who underwent single-plate Molteno implantation, with those achieved in a matched group who had trabeculectomy with postoperative 5-fluorouracil. Six months following surgery, the average intraocular pressure (IOP) in the Molteno group was 15.4 +/- 8.0 mm Hg, and in the trabeculectomy group, 16.1 +/- 5.6 mm Hg (P = .920). A mean of 1.4 antiglaucoma medications were being used in each group (P = .776). Complications following Molteno implantation included six tube revisions and three flat anterior chambers; following trabeculectomy, eight serous choroidal detachments and nine positive Seidel tests. This study suggests that Molteno implantation and trabeculectomy with adjunctive 5-fluorouracil provide similar IOP control, but that the two procedures are associated with different types of complications.
我们比较了连续22例行单盘Molteno植入术患者的治疗结果，以及与一组接受小梁切除术并术后使用5-氟尿嘧啶的匹配患者的治疗结果。术后6个月，Molteno组的平均眼压（IOP）为15.4±8.0 mmHg，小梁切除术组为16.1±5.6 mmHg（P = 0.920）。每组平均使用1.4种抗青光眼药物（P = 0.776）。Molteno植入术后的并发症包括6次引流管调整和3次无前房；小梁切除术后，8例浆液性脉络膜脱离和9次Seidel试验阳性。本研究表明，Molteno植入术和小梁切除术联合5-氟尿嘧啶在控制眼压方面效果相似，但这两种手术伴有不同类型的并发症。
