Hassmann-Poznańska E, Skotnicka B, Musiatowicz B, Hubert E
Klinika Otolaryngologii AM, Białymstoku.
Otolaryngol Pol. 1993;47(5):399-405.
19 patients with adenoid cystic carcinoma of the minor and major salivary glands were analysed clinicopathologically. Majority (8) of the tumours originated in the parotid gland. The palate was the most common location among the tumour of the minor salivary glands. The tumours were classified by their histology patterns into three groups: I tubular and cribriform pattern, II cribriform with less than 30% of solid pattern, III solid forms. A positive correlation between increasing grade and aggressive behavior was not observed in our study. All patients were treated with surgery. Eight of them received postsurgical radiation therapy. Recurrence of disease at the primary site occurred in 5 of 19 patients. Distant metastases developed in 3 patients. An adequate surgical excision of the tumour yields optimal local control and survival rates.
对19例小涎腺和大涎腺腺样囊性癌患者进行了临床病理分析。大多数(8例)肿瘤起源于腮腺。腭部是小涎腺肿瘤最常见的发病部位。根据组织学模式将肿瘤分为三组:I组为管状和筛状模式,II组为筛状且实性模式少于30%,III组为实性模式。在我们的研究中未观察到分级增加与侵袭性行为之间的正相关。所有患者均接受了手术治疗。其中8例接受了术后放射治疗。19例患者中有5例在原发部位出现疾病复发。3例患者发生远处转移。对肿瘤进行充分的手术切除可获得最佳的局部控制和生存率。