Wilson T E, Helvie M A, August D A
Department of Radiology, University of Michigan Hospitals, Ann Arbor 48109-0326.
Radiology. 1994 Jan;190(1):203-7. doi: 10.1148/radiology.190.1.8259405.
To determine the mammographic features and differences in stage of breast carcinomas in elderly women with malignancies detected with palpation or mammography at presentation.
The mammograms and clinical records of 60 patients (aged 75 years or older) with 62 breast carcinomas, detected during 40 consecutive months, were retrospectively reviewed. A variety of dedicated devices and processing equipment were used. The histologic features, mammographic appearance, mode of detection, and stage of disease were determined. Statistically significant differences between subgroups were calculated with the Student t and chi 2 tests.
Sixty cancers (97%) were seen on mammograms. Seventeen tumors detected with annual mammography differed significantly from the 45 carcinomas in nonscreened patients in diameter (1.1 vs 2.1 cm; P < .0005) and stage (14 minimal [82%] of 17 tumors vs 15 minimal [33%] of 45 tumors; P < .0005). Thirty-five nonpalpable malignancies differed significantly from 27 palpable masses in diameter (1.2 vs 2.3 cm; P = .01) and stage (25 tumors minimal [71%] vs four tumors minimal [15%]; P < .0005).
Screening mammography enabled detection of statistically significantly smaller and earlier-stage tumors, most of which were minimal disease.
确定在初诊时通过触诊或乳腺X线摄影检测出患有恶性肿瘤的老年女性乳腺癌的乳腺X线特征及分期差异。
回顾性分析连续40个月期间检测出的60例（年龄75岁及以上）患有62例乳腺癌患者的乳腺X线照片和临床记录。使用了各种专用设备和处理设备。确定组织学特征、乳腺X线表现、检测方式及疾病分期。采用Student t检验和卡方检验计算亚组间的统计学显著差异。
乳腺X线照片上发现60例癌症（97%）。通过年度乳腺X线摄影检测出的17个肿瘤与未进行筛查患者中的45个癌肿在直径（1.1对2.1 cm；P <.0005）和分期（17个肿瘤中有14个为微小癌[82%]，而45个肿瘤中有15个为微小癌[33%]；P <.0005）方面存在显著差异。35个不可触及的恶性肿瘤与27个可触及肿块在直径（1.2对2.3 cm；P =.01）和分期（25个肿瘤为微小癌[71%]，而4个肿瘤为微小癌[15%]；P <.0005）方面存在显著差异。
乳腺X线筛查能够检测出在统计学上显著更小且分期更早的肿瘤，其中大多数为微小癌。
