Daneschfar A, Davis C P, Trüeb R M
Dermatologische Klinik, Universität Zürich.
Schweiz Med Wochenschr. 1993 Oct 16;123(41):1941-4.
Hypertrichosis of the eyelashes was first described as "trichomegaly" in the setting of rare congenital syndromes. Recently numerous cases of acquired trichomegaly of the eyelashes have been described, especially in patients with advanced human immunodeficiency virus type I infection. The pathomechanisms leading to acquired trichomegaly remain largely unknown. Direct effects of the virus on the hair follicle, immune dysregulation, and a multifactorial pathogenesis are discussed. We report a case of acquired trichomegaly in advanced HIV-I infection in order to present this unusual clinical finding and other hair problems in AIDS patients. It is suggested that acquired trichomegaly of the eyelashes may act as a useful clinical marker for assessment of severity of HIV-I infection.
睫毛多毛症最初在罕见的先天性综合征背景下被描述为“睫毛粗大症”。最近，已报道了许多后天性睫毛粗大症病例，尤其是在晚期I型人类免疫缺陷病毒感染患者中。导致后天性睫毛粗大症的发病机制在很大程度上仍不清楚。文中讨论了病毒对毛囊的直接作用、免疫失调以及多因素发病机制。我们报告了一例晚期HIV-I感染患者出现后天性睫毛粗大症的病例，以展示这一不寻常的临床发现以及艾滋病患者的其他毛发问题。有人提出，后天性睫毛粗大症可能作为评估HIV-I感染严重程度的一个有用的临床指标。
