一名患有长QT综合征并同时服用阿司咪唑的年轻女性发生心脏骤停。
Cardiac arrest in a young woman with the long QT syndrome and concomitant astemizole ingestion.
作者信息
Broadhurst P, Nathan A W
机构信息
Department of Cardiology, St Bartholomew's Hospital, London.
出版信息
Br Heart J. 1993 Nov;70(5):469-70. doi: 10.1136/hrt.70.5.469.
Abstract
Ventricular fibrillation developed in a 19 year old woman taking the antihistamine astemizole. She was successfully resuscitated. QTc prolongation was found and persisted despite withdrawal of the drug. Aggravation of congenital long QTc syndrome by astemizole is postulated. More caution should be exercised with the use of this drug.
摘要
一名19岁服用抗组胺药阿司咪唑的女性发生了心室颤动。她成功复苏。尽管停用了该药物，但仍发现QTc延长且持续存在。推测阿司咪唑会加重先天性长QTc综合征。使用该药时应更加谨慎。
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