Sewing K F
Department of General Pharmacology, Medical School, Hannover, Germany.
J Physiol Pharmacol. 1993 Sep;44(3 Suppl 1):75-7.
The use of aluminium containing antacids raises the question of toxicity. Uptake of excessive quantities of aluminium may produce neurological symptoms and osteomalacia. Provided that renal function is intact ingested aluminium from antacids is absorbed to a small extent from the gastrointestinal tract resulting in a transient increase in plasma aluminium levels which never reach toxic concentration, and therefore can be regarded as safe.
含铝抗酸剂的使用引发了毒性问题。摄入过量铝可能会产生神经症状和骨软化症。只要肾功能完好,抗酸剂中的铝从胃肠道的吸收程度很小,只会导致血浆铝水平短暂升高,且永远不会达到中毒浓度,因此可以认为是安全的。