Chassot S, Lambert V, Kay A, Trépo C, Cova L
INSERM U 271, Lyon, France.
Arch Virol Suppl. 1993;8:133-9. doi: 10.1007/978-3-7091-9312-9_14.
The role of the immune response to the human hepatitis B virus (HBV) envelope proteins in neutralization of viral infectivity has been well documented. The similarity between HBV, prototype member of the hepadnavirus family, and the closely related duck hepatitis B virus (DHBV) has allowed, use of the latter as a convenient model for the study of molecular mechanisms of HBV replication and neutralization. In this brief review, we will examine the HBV and DHBV envelope proteins and their role as targets for virus neutralization.
免疫反应对人乙型肝炎病毒（HBV）包膜蛋白在中和病毒感染性方面的作用已有充分记载。嗜肝DNA病毒家族的原型成员HBV与密切相关的鸭乙型肝炎病毒（DHBV）之间的相似性，使得后者可作为研究HBV复制和中和分子机制的便捷模型。在这篇简短的综述中，我们将研究HBV和DHBV包膜蛋白及其作为病毒中和靶点的作用。
