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临终关怀患者预期寿命的预测:新型预后因素的识别。

Prediction of life-expectancy in hospice patients: identification of novel prognostic factors.

作者信息

Rosenthal M A, Gebski V J, Kefford R F, Stuart-Harris R C

机构信息

Department of Medical Oncology, Westmead Hospital, Australia.

出版信息

Palliat Med. 1993;7(3):199-204. doi: 10.1177/026921639300700306.

Abstract

The prediction of life-expectancy in terminally ill patients is important both for medical and social reasons but is widely recognized as being inaccurate. In this study we prospectively collected data items which we proposed might influence survival on 148 consecutive patients at first admission to one of two hospices. Of the 19 parameters collected, four were associated with a significantly shortened survival. These were low performance status (PS), requirement for admission at first referral to the palliative care service, elevated serum bilirubin, and hypotension. Factors previously identified as predictive of shortened survival such as hyponatraemia, weight loss, confusion and tumour type were not confirmed as statistically significant independent variables. We plan to collect these data items on future patients in order to test the validity of these results.

摘要

出于医学和社会原因,对晚期患者的预期寿命进行预测很重要,但人们普遍认为这种预测并不准确。在本研究中,我们前瞻性地收集了148例连续首次入住两家临终关怀机构之一的患者的数据项目,我们认为这些项目可能会影响生存。在收集的19个参数中,有4个与生存期显著缩短相关。这些参数是低体能状态(PS)、首次转诊至姑息治疗服务时的入院需求、血清胆红素升高和低血压。先前被确定为生存期缩短预测因素的因素,如低钠血症、体重减轻、意识模糊和肿瘤类型,未被确认为具有统计学意义的独立变量。我们计划在未来的患者中收集这些数据项目,以检验这些结果的有效性。

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