Paterson K R
Diabetes Centre, Royal Infirmary, Glasgow, UK.
Diabet Med. 1993 Oct;10(8):777-81. doi: 10.1111/j.1464-5491.1993.tb00164.x.
The role and value of screening for diabetes mellitus is still unclear. If asymptomatic subjects are to be screened, then a fasting plasma glucose > 6.6 mmol l-1 or a venous plasma glucose 2 h after a 75 g oral glucose load > 8.0 mmol l-1 or the presence of any glucose in a urine sample passed 2 h after a main meal should be regarded as a positive result. A fasting plasma glucose in the range 5.5-6.6 mmol l-1 is an equivocal result which should lead to retesting in 6-12 months if there is any risk factor for diabetes (obesity, family history of diabetes, Asian/African racial origin). Other screening tests or combinations of tests are not recommended. Screening should be restricted to subjects between 40 and 75 years and should be undertaken only every 5 years (3 years if a risk factor for diabetes is present), ideally in parallel with other health screening test; subjects with a positive result should have further investigations as necessary to reach a diagnosis in line with WHO criteria.
糖尿病筛查的作用和价值仍不明确。如果要对无症状受试者进行筛查，那么空腹血糖>6.6 mmol/L、75 g口服葡萄糖负荷后2小时静脉血浆葡萄糖>8.0 mmol/L或主餐后2小时尿液样本中存在任何葡萄糖，都应视为阳性结果。空腹血糖在5.5 - 6.6 mmol/L之间为可疑结果，如果存在糖尿病危险因素（肥胖、糖尿病家族史、亚洲/非洲种族出身），则应在6 - 12个月后重新检测。不推荐使用其他筛查试验或试验组合。筛查应限于40至75岁的受试者，且仅每5年进行一次（如果存在糖尿病危险因素则每3年进行一次），理想情况下应与其他健康筛查试验同时进行；结果呈阳性的受试者应根据需要进行进一步检查，以根据世界卫生组织标准做出诊断。
