Padhy R N, Singh P K
Arch Virol. 1976;52(1-2):85-90. doi: 10.1007/BF01317867.
The spontaneous and nitrosoguanidine induced N-1 virus resistant mutants of the blue-green alga Nostoc muscorum were isolated with the average mutation frequency of 3.55 X 10(-5) and 6.08 X 10(-4) respectively. Of the surviving colonies 8 per cent became virus sensitive,whereas out of the remaining 92 per cent 9.3 per cent showed lysogenic behaviour and 13.3 per cent showed poor or no nitrogen fixing ability. Mutation to virus-resistance was independent of the presence of the virus.Spontaneous host range mutants of virus were not found in repeated experiments.
从蓝藻地木耳中分离出了自发产生的和经亚硝基胍诱导产生的抗N-1病毒突变体,其平均突变频率分别为3.55×10⁻⁵和6.08×10⁻⁴。在存活的菌落中,8%对病毒敏感,而在其余92%中,9.3%表现出溶原性行为,13.3%表现出固氮能力差或无固氮能力。对病毒抗性的突变与病毒的存在无关。在重复实验中未发现病毒的自发宿主范围突变体。