The effect of phorbol ester treatment on migration of C3H 10T1/2 and BT5C glioma cells: possible application to carcinogenesis.
作者信息
Janik P, Szaniawska B, Kowalczyk D, Miłoszewska J
机构信息
Department of Tumor Biology, Cancer Center, Warsaw, Poland.
出版信息
J Cancer Res Clin Oncol. 1994;120(3):156-8. doi: 10.1007/BF01202194.
Abstract
Treatment with the tumor-promoting phorbol ester 12-O-tetradecanoylphorbol 13-acetate (TPA) and the second-stage promoter 12-O-retinoylphorbol 13-acetate induced down-regulation of protein kinase C (PKC) and enhanced the migration of C3H 10T1/2 cells. In the case of BT5C glioma cells the same negative correlation was observed only after treatment with TPA. The negative control 4 alpha-phorbol affected neither PKC activity nor the migratory ability of both cell lines.
摘要
相似文献
1
The effect of phorbol ester treatment on migration of C3H 10T1/2 and BT5C glioma cells: possible application to carcinogenesis.
J Cancer Res Clin Oncol. 1994;120(3):156-8. doi: 10.1007/BF01202194.
2
Induction of Epstein-Barr virus early antigens by tumor promoters of the diterpene ester type in Raji cells and specific (receptor) binding as compared to irritant and promoting activities.
J Cancer Res Clin Oncol. 1989;115(2):148-56. doi: 10.1007/BF00397915.
3
Promoting phorbol ester-TPA enhances migration of C3H 10T1/2 cells. The role of protein kinase C and its relation to carcinogenesis.
Folia Biol (Krakow). 1995;43(3-4):83-7.
4
Differential effects of 12-O-tetradecanoyl-13-phorbol acetate (TPA) on growth, migration and invasion of a human glioma cell line.
Anticancer Res. 1993 Sep-Oct;13(5A):1325-30.
5
Induction of differentiation in human promyelocytic leukemia cells by tumor promoters.
J Cancer Res Clin Oncol. 1982;103(1):17-29. doi: 10.1007/BF00410302.
6
Overproduction of the beta 1 form of protein kinase C enhances phorbol ester induction of glucose transporter mRNA.
Mol Endocrinol. 1989 Dec;3(12):2018-27. doi: 10.1210/mend-3-12-2018.
7
Effect of phorbol esters on the susceptibility of a glioma cell line to lymphokine-activated killer cell activity.
J Neurosurg. 1990 Jul;73(1):91-7. doi: 10.3171/jns.1990.73.1.0091.
8
Early changes in the arachidonic acid metabolism of HeLa cells in response to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) and related compounds.
J Cancer Res Clin Oncol. 1987;113(2):137-44. doi: 10.1007/BF00391435.
9
The pleiotropic effect of TPA on in vitro invasion/migration of glioma and melanoma cell lines.
Cancer Lett. 1996 Oct 22;107(2):205-9. doi: 10.1016/0304-3835(96)04369-8.
10
Inhibition of growth of established human glioma cell lines by modulators of the protein kinase-C system.
J Neurosurg. 1990 Oct;73(4):594-600. doi: 10.3171/jns.1990.73.4.0594.
引用本文的文献
1
Gelsolin suppresses tumorigenicity through inhibiting PKC activation in a human lung cancer cell line, PC10.
Br J Cancer. 2003 Feb 24;88(4):606-12. doi: 10.1038/sj.bjc.6600739.
本文引用的文献
1
Investigation of the mechanism for enhancement of radiation transformation in vitro by 12-O-tetradecanoylphorbol-13-acetate.
Carcinogenesis. 1980;1(12):1039-47. doi: 10.1093/carcin/1.12.1039.
2
Protein kinase C: a novel target for inhibiting gastric cancer cell invasion.
J Natl Cancer Inst. 1993 Mar 3;85(5):402-7. doi: 10.1093/jnci/85.5.402.
3
Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.
J Biol Chem. 1982 Jul 10;257(13):7847-51.
4
Isolation of methylcholanthrene-"initiated" C3H/10T1/2 cells by inhibiting neoplastic progression with retinyl acetate.
Carcinogenesis. 1982;3(3):279-85. doi: 10.1093/carcin/3.3.279.
5
Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane.
Nature. 1983;301(5901):621-3. doi: 10.1038/301621a0.
6
Soluble phorbol ester binding sites and phospholipid- and calcium-dependent protein kinase activity in cytosol of chick oviduct.
FEBS Lett. 1983 Oct 3;162(1):147-50. doi: 10.1016/0014-5793(83)81067-9.
7
Disappearance of Ca2+-sensitive, phospholipid-dependent protein kinase activity in phorbol ester-treated 3T3 cells.
Biochem Biophys Res Commun. 1984 May 16;120(3):1053-9. doi: 10.1016/s0006-291x(84)80213-2.
8
The role of protein kinase C in cell surface signal transduction and tumour promotion.
Nature. 1984;308(5961):693-8. doi: 10.1038/308693a0.
9
10
Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division.
Cancer Res. 1973 Dec;33(12):3231-8.
Zotero 插件