Kuruvilla A, Srikrishna G, Peedicayil J, Kuruvilla K, Kanagasabapathy A S
Department of Pharmacology, Christian Medical and Hospital, Vellore, India.
Int Clin Psychopharmacol. 1993 Fall;8(3):177-9. doi: 10.1097/00004850-199300830-00007.
Serum prolactin levels are determined in 116 schizophrenics and 120 control subjects. Values of prolactin levels of the patients are compared with the values of control of the same sex and age group. There is no significant difference between prolactin levels of controls and those with negative or positive symptoms of schizophrenia. Analysis, taking age into account, also does not show any significant difference between patients with positive or negative symptoms and controls. The relationship between nature of symptoms of schizophrenia and serum prolactin levels varies in different studies. The possible reasons for such variations are discussed.
对116名精神分裂症患者和120名对照者测定血清催乳素水平。将患者的催乳素水平值与相同性别和年龄组对照者的值进行比较。精神分裂症对照组与有阴性或阳性症状者的催乳素水平之间无显著差异。在考虑年龄的分析中,有阳性或阴性症状的患者与对照组之间也未显示出任何显著差异。精神分裂症症状性质与血清催乳素水平之间的关系在不同研究中有所不同。讨论了出现这种差异的可能原因。