Faddy M J
Department of Mathematics, University of Queensland, Australia.
IMA J Math Appl Med Biol. 1993;10(3):179-86. doi: 10.1093/imammb/10.3.179.
A diffusion approximation is developed for one-compartment systems with nonlinear elimination rates. Both impulsive input and continuous infusion are considered. Explicit expressions for the mean and autocovariance functions of the contents of the compartment as time elapses are given.
针对具有非线性消除率的单室系统建立了扩散近似。同时考虑了脉冲输入和连续输注。给出了随着时间推移该室内容物的均值和自协方差函数的显式表达式。
