Krupala J L, Gianoli G J
Tulane Medical Center, Dept of Otolaryngology-Head & Neck Surgery, New Orleans.
J La State Med Soc. 1993 Oct;145(10):421-2, 425-6.
Carcinoma of the oral tongue is the second most common malignancy of the oral cavity. Major risk factors include tobacco and alcohol usage. Early diagnosis is the cornerstone of successful management. Comprehensive evaluation and treatment modalities are reviewed. For early lesions, surgery or radiation therapy may be employed with equal efficacy. For advanced lesions, combination radiotherapy and surgery are advocated. Chemotherapy is still experimental, but continues to undergo multicenter investigations for treatment of oral tongue carcinoma.
口腔舌癌是口腔中第二常见的恶性肿瘤。主要危险因素包括吸烟和饮酒。早期诊断是成功治疗的基石。本文综述了综合评估和治疗方式。对于早期病变,手术或放射治疗的疗效相当。对于晚期病变,提倡放疗与手术联合应用。化疗仍处于试验阶段,但仍在进行多中心研究以治疗口腔舌癌。