Pelaprat D, Oberlin R, Roques B P, Le Pecq J B
C R Acad Hebd Seances Acad Sci D. 1976 Oct 18;283(9):1109-12.
7 H, 10-methoxy pyrido [3,2-c], [4,3-c] and [3,4-c] carbazoles, and 7 H-pyrido [2,3-c] carbazole were synthesized by oxidative photocyclisation, to achieve a topological analysis of intercalation in DNA. From these parent compounds we have prepared the corresponding iodomethylates, 7-methyl and 10-hydroxy derivatives.
通过氧化光环化反应合成了7H,10-甲氧基吡啶并[3,2-c]、[4,3-c]和[3,4-c]咔唑以及7H-吡啶并[2,3-c]咔唑，以实现对DNA嵌入的拓扑分析。从这些母体化合物出发，我们制备了相应的碘甲基化物、7-甲基和10-羟基衍生物。
