Shearer D E, Fleming D E, Bigler E D
Epilepsia. 1976 Dec;17(4):429-35. doi: 10.1111/j.1528-1157.1976.tb04455.x.
Lightly restrained albino rats were administered dipropylacetic acid, trimethadione, diphenylhydantoin, saline, and a pentylenetetrazol challenge. The results were attributed to the locus of action of the anticonvulsants and strongly support the usefulness of the photically evoked after discharge as a model for the evaluation of thalamically active drugs, with particular reference to those useful in the control of petit mal epilepsy.
对轻度束缚的白化病大鼠给予二丙基乙酸、三甲双酮、苯妥英、生理盐水，并进行戊四氮激发试验。结果归因于抗惊厥药的作用部位，并有力地支持了光诱发后放电作为评估丘脑活性药物模型的实用性，特别是对于那些对控制失神性癫痫有效的药物。
