Yap I, Guan R, Kang J Y, Gwee K A, Tan C C
Department of Medicine, National University Hospital, Singapore.
Singapore Med J. 1993 Jun;34(3):257-8.
We describe nine cases of esophageal injury associated with the ingestion of prescribed medications. Antibiotics were the most commonly implicated drugs. Odynophagia, retrosternal chest pain and dysphagia were the usual presenting symptoms. The typical endoscopic finding was that of discrete ulcers in the mid-esophagus. All patients recovered uneventfully with discontinuation of the offending drug and symptomatic treatment. Drug induced esophageal injury should be considered in patients presenting acutely with the above mentioned symptoms and having discrete esophageal ulcers on endoscopy.
我们描述了9例与服用处方药相关的食管损伤病例。抗生素是最常涉及的药物。吞咽疼痛、胸骨后胸痛和吞咽困难是常见的症状。典型的内镜检查发现是食管中段有散在溃疡。所有患者停用致病药物并进行对症治疗后均顺利康复。对于急性出现上述症状且内镜检查发现食管有散在溃疡的患者,应考虑药物性食管损伤。