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阑尾腺癌的流式细胞术DNA分析。简要报告。

Flow cytometric DNA analysis of adenocarcinomas of the vermiform appendix. Brief report.

作者信息

Nielsen G P, Jónasson J G, Agnarsson B A, Isaksson H J

机构信息

Department of Pathology, University of Iceland.

出版信息

APMIS. 1993 Oct;101(10):811-4. doi: 10.1111/j.1699-0463.1993.tb00185.x.

Abstract

The DNA ploidy status and S-phase fraction of eight adenocarcinomas of the vermiform appendix diagnosed in Iceland during 1974-1990 were analyzed by flow cytometry. Four cases were classified as Dukes' stage B2 and four cases as Dukes' stage D. Seven tumors were diploid and one was aneuploid. The DNA aneuploid tumor was the only one which metastasized outside the abdominal cavity. The S-phase fraction in general was low. The results of this study do not indicate any significant correlation between ploidy status and clinical behavior.

摘要

对1974年至1990年间在冰岛诊断出的8例阑尾腺癌的DNA倍体状态和S期分数进行了流式细胞术分析。4例被归类为杜克B2期,4例为杜克D期。7个肿瘤为二倍体,1个为非整倍体。DNA非整倍体肿瘤是唯一发生腹腔外转移的肿瘤。总体S期分数较低。本研究结果未表明倍体状态与临床行为之间存在任何显著相关性。

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