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一例原发性肠淋巴管扩张症。

A case of primary intestinal lymphangiectasia.

作者信息

Won K C, Jang B I, Kim T N, Lee H W, Chung M K, Lee H W

机构信息

Department of Internal Medicine, College of Medicine, Yeungnam University, Taegu, Korea.

出版信息

Korean J Intern Med. 1993 Jan;8(1):51-5. doi: 10.3904/kjim.1993.8.1.51.

DOI:10.3904/kjim.1993.8.1.51
PMID:8268148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4532082/
Abstract

A 26-year-old male patient who had an 8 years history of recurrent peripheral edema with diarrhea and hypoproteinemia was evaluated. Endoscopic jejunal and ileal biopsy revealed markedly dilated mucosal lymph vessels with no evidence of inflammation. 99mTc-labeled human serum albumin (HSA) scintigraphy showed significant activity accumulating in the gastrointestinal tract to represent 99mTc-HSA leakage into the bowel lumen. A diagnosis of protein losing enteropathy and intestinal lymphangiectasia could be made. After treatment with a high protein and fat restricted diet, his symptoms subsided and the serum protein level was normalized.

摘要

一名26岁男性患者,有8年复发性外周水肿伴腹泻和低蛋白血症病史,接受了评估。内镜下空肠和回肠活检显示黏膜淋巴管明显扩张,无炎症迹象。99mTc标记的人血清白蛋白(HSA)闪烁扫描显示胃肠道有大量放射性积聚,提示99mTc-HSA漏入肠腔。可诊断为蛋白丢失性肠病和肠淋巴管扩张症。经过高蛋白和低脂饮食治疗后,他的症状缓解,血清蛋白水平恢复正常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/889a/4532082/e36123d710a2/kjim-8-1-51-10f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/889a/4532082/6530feb2fd2c/kjim-8-1-51-10f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/889a/4532082/6a24d39c6ade/kjim-8-1-51-10f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/889a/4532082/f9b1c1272e8f/kjim-8-1-51-10f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/889a/4532082/e36123d710a2/kjim-8-1-51-10f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/889a/4532082/6530feb2fd2c/kjim-8-1-51-10f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/889a/4532082/6a24d39c6ade/kjim-8-1-51-10f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/889a/4532082/f9b1c1272e8f/kjim-8-1-51-10f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/889a/4532082/e36123d710a2/kjim-8-1-51-10f4.jpg

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引用本文的文献

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Lymphangiomatosis of the ileum with perforation: A case report and review of the literature.回肠淋巴管瘤病合并穿孔:一例报告及文献复习
Ann Med Surg (Lond). 2019 Mar 29;41:6-10. doi: 10.1016/j.amsu.2019.03.010. eCollection 2019 May.

本文引用的文献

1
Protein-losing disorders of the gastrointestinal tract: roentgen features.胃肠道蛋白质丢失性疾病:X线表现
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2
Hypoproteinemia antedating intestinal lesions, and possibly due to excessive serum protein loss into the intestine.低蛋白血症早于肠道病变出现,可能是由于血清蛋白过多丢失至肠道所致。
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THE MEASUREMENT OF ALBUMIN LEAK INTO THE GASTROINTESTINAL TRACT USING 131-I-ALBUMIN AND ION EXCHANGE RESIN BY MOUTH.口服¹³¹I-白蛋白和离子交换树脂测定白蛋白向胃肠道的渗漏情况。
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7
SYSTEMIC LYMPHATIC ABNORMALITIES ASSOCIATED WITH GASTROINTESTINAL PROTEIN LOSS SECONDARY TO INTESTINAL LYMPHANGIECTASIA.与继发于肠淋巴管扩张症的胃肠道蛋白丢失相关的系统性淋巴异常。
Gastroenterology. 1963 Dec;45:703-11.
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Protein-losing enteropathy.蛋白丢失性肠病
Gastroenterology. 1966 Mar;50(3):422-43.
10
Immunodeficiency disease and malignancy. Various immunologic deficiencies of man and the role of immune processes in the control of malignant disease.免疫缺陷疾病与恶性肿瘤。人类的各种免疫缺陷以及免疫过程在恶性疾病控制中的作用。
Ann Intern Med. 1972 Oct;77(4):605-28.