Downer M C
Insitute of Dental Surgery, Eastman Dental Hospital, London, UK.
Community Dent Health. 1993 Sep;10 Suppl 2:39-46.
An expert panel examining future goals for oral and dental health services research in the United States, considered that high on the list of priorities should be investigations of public health solutions for the control of those diseases which are of low prevalence but high morbidity and mortality such as oral cancer, and those which are of high prevalence and social impact but which represent a lesser threat to health such as dental caries. Against the background of demographic population changes, the present overview first examines trends in caries experience in the United Kingdom and their research implications, and then trends in oral cancer and precancer. It is suggested that an opportunistic screening programme for the latter conditions could be a cost-effective, feasible and appropriate approach to their prevention. An existing computer simulation model for undertaking cost evaluation studies of alternative interventions is discussed and it is concluded that such a model could provide useful background data before a national pilot study of screening for oral cancer and precancer were embarked upon.
一个研究美国口腔健康服务研究未来目标的专家小组认为，优先事项清单中应排在前列的是对控制那些低患病率但高发病率和高死亡率的疾病（如口腔癌）以及那些高患病率和社会影响但对健康威胁较小的疾病（如龋齿）的公共卫生解决方案进行调查。在人口结构变化的背景下，本综述首先考察英国龋齿情况的趋势及其研究意义，然后考察口腔癌和癌前病变的趋势。有人建议，针对后一种情况的机会性筛查计划可能是预防它们的一种具有成本效益、可行且合适的方法。讨论了一个现有的用于对替代干预措施进行成本评估研究的计算机模拟模型，并得出结论，在开展全国性口腔癌和癌前病变筛查试点研究之前，这样一个模型可以提供有用的背景数据。
