Tinklenberg J R, Roth W T, Kopell B S
Psychopharmacology (Berl). 1976 Sep 29;49(3):275-9. doi: 10.1007/BF00426830.
Performance on a time production task, heart rate, and subjective responses were studied in twelve male sujects given oral doses of marijuana (0.7 mg of delta-9-tetrahydrocannabinol/kg), ethanol (1.0 ml/kg), and placebo, on three testing days which were each separated by 1 week. Orders were balanced across subjects and testing conditions were double-blind. Compared to ethanol and placebo, marijuana induced a significant under-production of time intervals, suggesting an acceleration of the internal rate of time perception. The onset of this acceleration of time sense in which geophysical time seemed to pass slowly corresponded with the characteristic increase in heart rate and the onset of the subjective feelings of drug effects. Initial phases of alcohol intoxication were associated with the opposite effects on the time production task. These findings replicate previous work and indicate that an easily administered time production task provides a consistent, non-motor measure of acute marijuana intoxication and also reflects ethanol intoxication.
在三个相隔1周的测试日，对12名口服大麻（0.7毫克δ-9-四氢大麻酚/千克）、乙醇（1.0毫升/千克）和安慰剂的男性受试者进行了时间生产任务表现、心率和主观反应的研究。顺序在受试者间进行了平衡，测试条件为双盲。与乙醇和安慰剂相比，大麻导致时间间隔显著减少，表明时间感知的内部速率加快。这种时间感加速的开始，即地球物理时间似乎过得很慢，与心率的特征性增加以及药物效应主观感受的开始相对应。酒精中毒的初始阶段对时间生产任务有相反的影响。这些发现重复了先前的研究工作，并表明一个易于实施的时间生产任务为急性大麻中毒提供了一种一致的、非运动性的测量方法，也反映了乙醇中毒。
