Cammermeyer J
Acta Anat (Basel). 1976;96(3):459-68. doi: 10.1159/000144694.
When mast cells, identified by metachromatic color in cresyl-echt-violet-stained paraffin sections, aggregate in large numbers, the intensity of cytoplasmic granulation varies. The intensely stained cytoplasmic granules of heavily granulated cells may be pushed over the microscopic section by the microntome blade either in the direction of cutting or against it. In the pale mast cells, in which a progressive pyknosis and atrophy of the nuclei by compaction of DNA particles take place, dislodgment and displacement of the pyknotic nuclei may occur in 1.1-2.3% of these cells. The pyknotic nuclei are expelled, usually in the direction of cutting, and deposited on top of the mi-roscopic section at various distances from their original site. While this expulsion is regarded as artifactitious, caused by the mechanical actioh of the microtome blade, the nuclear pyknosis, which is a prerequisite, is associated with intravital alterations.
当在甲酚紫染色的石蜡切片中通过异染性颜色鉴定出的肥大细胞大量聚集时，细胞质颗粒化的强度会有所不同。重度颗粒化细胞中染色强烈的细胞质颗粒可能会被切片机刀片在切片方向或与之相反的方向推过显微镜切片。在苍白的肥大细胞中，由于DNA颗粒的压实会发生细胞核进行性固缩和萎缩，在这些细胞中，1.1%-2.3%可能会出现固缩核的移位和位移。固缩核通常沿切片方向被排出，并沉积在显微镜切片上距其原始位置不同距离处。虽然这种排出被认为是由切片机刀片的机械作用导致的人为现象，但作为前提条件的核固缩与活体改变有关。
