猫延髓中缝核群呼吸神经元的放电模式及位置

Firing pattern and location of respiratory neurons in cat medullary raphe nuclei.

作者信息

Hosogai M, Matsuo S, Nakao S

机构信息

Department of Physiology, Faculty of Medicine, Tottori University, Yonago, Japan.

出版信息

Neurosci Lett. 1993 Oct 29;161(2):149-52. doi: 10.1016/0304-3940(93)90281-o.

DOI:10.1016/0304-3940(93)90281-o

PMID:8272256

Abstract

Extracellular spikes of single respiratory neurons were explored in the medullary raphe nuclei in spontaneously breathing decerebrated or Nembutal-anesthetized cats. A total of 26 respiratory neurons, whose spikes were confirmed to originate from the cell bodies, was recorded in the raphe obscurus and pallidus. They could be classified into six types based on the relation of their firing to the phases of respiration: (1) inspiratory (I) decrementing (I-DEC, n = 14), (2) I-frequency modulated (n = 3), (3) I-augmenting (I-AUG, n = 2), (4) late I (n = 2), (5) expiratory (E) augmenting (E-AUG, n = 3) and (6) I-E phase-spanning (I-E PS, n = 2). These results suggest the existence of neurons relating to the control of respiration in the medullary raphe nuclei.

摘要

在自主呼吸的去大脑或戊巴比妥麻醉的猫的延髓中缝核中，对单个呼吸神经元的细胞外峰电位进行了研究。在中缝隐核和中缝苍白核中，共记录到26个呼吸神经元，其峰电位被证实起源于细胞体。根据其放电与呼吸相位的关系，它们可分为六种类型：(1)吸气(I)递减型(I-DEC，n = 14)，(2)I-频率调制型(n = 3)，(3)I-增强型(I-AUG，n = 2)，(4)晚期吸气型(n = 2)，(5)呼气(E)增强型(E-AUG，n = 3)和(6)吸气-呼气跨相型(I-E PS，n = 2)。这些结果表明，延髓中缝核中存在与呼吸控制有关的神经元。