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伴有着色性干皮病的结膜恶性黑色素瘤

Conjunctival malignant melanoma with xeroderma pigmentosum.

作者信息

Aoyagi M, Morishima N, Yoshino Y, Imagawa N, Kiyosawa M, Ito M, Kondou S, Matsubara O

机构信息

Department of Ophthalmology, School of Medicine, Tokyo Medical and Dental University, Japan.

出版信息

Ophthalmologica. 1993;206(3):162-7. doi: 10.1159/000310384.

DOI:10.1159/000310384
PMID:8272340
Abstract

A 10-year-old male patient with xeroderma pigmentosum had a recurrent, pigmented, conjunctival tumor. Conjunctival malignant melanoma was diagnosed from the histopathological examination of the resected biopsy specimens. To our knowledge, this case of conjunctival malignant melanoma in a patient with xeroderma pigmentosum may be the second such report in the literature. We believe that malignant melanoma must be considered with squamous cell carcinoma in the differential diagnosis of conjunctival tumors in patients with xeroderma pigmentosum. Fontana-Masson and S-100 staining techniques helped diagnose this conjunctival malignant melanoma.

摘要

一名患有着色性干皮病的10岁男性患者出现复发性色素性结膜肿瘤。经对切除的活检标本进行组织病理学检查,诊断为结膜恶性黑色素瘤。据我们所知,该例着色性干皮病患者的结膜恶性黑色素瘤可能是文献中的第二例此类报告。我们认为,在着色性干皮病患者结膜肿瘤的鉴别诊断中,必须将恶性黑色素瘤与鳞状细胞癌一并考虑。Fontana-Masson和S-100染色技术有助于诊断该结膜恶性黑色素瘤。

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引用本文的文献

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Pediatric conjunctival melanoma: A comprehensive case report and literature review.小儿结膜黑色素瘤:一份全面的病例报告及文献综述
Am J Ophthalmol Case Rep. 2024 May 22;35:102075. doi: 10.1016/j.ajoc.2024.102075. eCollection 2024 Sep.
2
Conjunctival Melanoma in Childhood and Adolescence: A Systematic Review.儿童及青少年结膜黑色素瘤:一项系统综述
Ocul Oncol Pathol. 2019 Oct;5(6):387-395. doi: 10.1159/000497813. Epub 2019 Apr 10.
3
Ophthalmic manifestations and histopathology of xeroderma pigmentosum: two clinicopathological cases and a review of the literature.
着色性干皮病的眼部表现和组织病理学:两例临床病理病例及文献复习。
Surv Ophthalmol. 2011 Jul-Aug;56(4):348-61. doi: 10.1016/j.survophthal.2011.03.001.
4
Inflamed juvenile conjunctival naevus: clinicopathological characterisation.炎症性青少年结膜痣:临床病理特征
Br J Ophthalmol. 2002 Jan;86(1):28-30. doi: 10.1136/bjo.86.1.28.
5
Conjunctival melanoma: risk factors for recurrence, exenteration, metastasis, and death in 150 consecutive patients.结膜黑色素瘤:150例连续患者复发、眼眶内容剜除术、转移及死亡的危险因素
Trans Am Ophthalmol Soc. 2000;98:471-92.