Guarente L
Department of Biology, Massachusetts Institute of Technology, Cambridge 02139.
Trends Genet. 1993 Oct;9(10):362-6. doi: 10.1016/0168-9525(93)90042-g.
Synthetic enhancement, in which one mutation exacerbates the severity of another, is a genetic interaction of increasing importance in biology. This review focuses on the logic of interpreting synthetic enhancement, and begins by comparing the phenomenon with genetic suppression.
合成增强是指一个突变会加剧另一个突变的严重程度,这是一种在生物学中重要性日益增加的基因相互作用。本综述重点关注解释合成增强的逻辑,并首先将该现象与基因抑制进行比较。