Sarkisova K Iu, Kolomeĭtseva I A
Biull Eksp Biol Med. 1993 Aug;116(8):130-2.
Resistance (predisposition) to behavior and sleep disturbances after acute stress was studied in rats with different types of behavior in open field and forced swimming tests. The highest resistance to stress (the least alterations of behavior and sleep parameters) was found in rats with the active type of behavior, the least resistance to stress--in the middle group, and rats with the passive type of behavior held the intermediate position. The comparison of the present data with previously obtained results showed a positive correlation between the resistance to stress and the resistance to circulatory cerebral hypoxia induced by bilateral common carotid arteries occlusion. The biological significance of the association of resistance to stress and to cerebral hypoxia with the type of behavior is discussed.
在旷场试验和强迫游泳试验中,对具有不同行为类型的大鼠在急性应激后对行为和睡眠障碍的抵抗力(易感性)进行了研究。在具有活跃行为类型的大鼠中发现对应激的抵抗力最高(行为和睡眠参数的改变最少),对应激的抵抗力最低的是中间组,而具有被动行为类型的大鼠则处于中间位置。将目前的数据与先前获得的结果进行比较,结果显示应激抵抗力与双侧颈总动脉闭塞诱导的循环性脑缺氧抵抗力之间存在正相关。讨论了应激抵抗力和脑缺氧抵抗力与行为类型之间关联的生物学意义。