Barkova E N, Gurov O V, Gurova O P
Biull Eksp Biol Med. 1993 Aug;116(8):147-9.
Experiments with male California rabbits were carried out different intervals of acute alcohol intoxication induced by intragastric administration of 40% ethanol solution in a dose of 10 ml/kg to examine daily changes of concentration of iron, alpha-tocopherol and lipid peroxidation products in the blood plasma from vena portal and vena hepatis. Acute alcohol intoxication was demonstrated to be accompanied by inversion in temporal organization of lipid peroxidation products, sideremia and alpha-tocopherol levels in the blood of vena hepatis. The invariability of the circadian rhythms of iron, alpha-tocopherol and lipid peroxidation products levels in vena portal blood a considered to prove participation of the liver in regulation of iron metabolism temporal organization in California rabbits with acute alcohol intoxication.
对雄性加利福尼亚兔进行实验，通过胃内给予剂量为10 ml/kg的40%乙醇溶液诱导不同间隔时间的急性酒精中毒，以检测门静脉和肝静脉血浆中铁、α-生育酚和脂质过氧化产物浓度的每日变化。结果表明，急性酒精中毒伴随着肝静脉血液中脂质过氧化产物、铁血症和α-生育酚水平的时间组织倒置。门静脉血液中铁、α-生育酚和脂质过氧化产物水平的昼夜节律不变，被认为证明了肝脏参与了急性酒精中毒的加利福尼亚兔铁代谢时间组织的调节。
