Seltzer D G, Brown M D, Tompkins J S, Enger I, Cammisa F P
Department of Sports Medicine and Shoulder Surgery, Maricopa County Medical Center, Arizona 85010.
J Spinal Disord. 1993 Oct;6(5):412-21. doi: 10.1097/00002517-199306050-00008.
Two hundred twenty-four consecutive patients underwent elective posterior lumbar spinal surgery over a 3 1/2-year span at the University of Miami/Jackson Memorial Medical Center. Patients ranged in age from 17 to 87 years, and 58% were male. Fifty-eight patients underwent revision surgery, and 65 patients required fusions, including 35 necessitating internal fixation. One hundred seventy-four patients (78%) were requested to participate in a preoperatively donated autologous blood (PDAB) program. Six of these patients were excluded from participation, and 168 patients banked 425 U of autologous blood. Eighty percent of the patients participating in the PDAB program received some or all of their donated blood. Intraoperative blood salvage was used in 37% of cases. Seven patients received homologous blood: four in addition to salvaged and donated blood, two that were unable to donate blood due to positive hepatitis B serology, and one erroneously. The combined use of PDAB and intraoperative salvage program allowed autologous blood replacement to meet the total transfusion requirements of 96% of the patients who predeposited blood, including 94% of those undergoing spinal fusions. Autologous blood comprised 99% of the total blood replacement used in this series, and 95% of the patients requiring blood transfusions received only autologous blood. Establishment of a protocol judiciously using PDAB in conjunction with intraoperative blood salvage can result in virtual elimination of the need for homologous blood transfusion in elective lumbar spine surgery.
在迈阿密大学/杰克逊纪念医学中心,224例连续患者在3年半的时间里接受了择期腰椎后路手术。患者年龄在17至87岁之间,58%为男性。58例患者接受了翻修手术,65例患者需要进行融合手术,其中35例需要内固定。174例患者(78%)被要求参与术前自体血预存(PDAB)项目。其中6例患者被排除在外,168例患者储存了425单位的自体血。参与PDAB项目的患者中有80%接受了部分或全部所捐献的血液。37%的病例使用了术中血液回收。7例患者接受了异体血:4例除回收血和捐献血外还接受了异体血,2例因乙肝血清学阳性无法献血,1例为误输。PDAB与术中回收项目的联合使用使自体血替代能够满足96%预存血液患者的总输血需求,包括94%接受脊柱融合手术的患者。自体血占本系列中使用的总输血替代量的99%,95%需要输血的患者仅接受自体血。明智地使用PDAB并结合术中血液回收制定方案,可以在择期腰椎手术中几乎消除对异体输血的需求。