Picciocchi A, Granone P, Cardillo G, Margaritora S, Benzoni C, D'Ugo D
Department of General Surgery A Gemelli Medical School, Catholic University of Rome, Italy.
Int Surg. 1993 Jul-Sep;78(3):221-4.
Since January 1987, in a consecutive series of 56 resections of the chest-wall for cancer, the wall defect was repaired by a prosthetic implant on 14 occasions (10 silastic sheeting, 4 goretex soft tissue patch). Indications for thoracic wall resection were: T3 primary lung cancers (7 cases), local recurrences after breast cancer surgery (5 cases), primary and metastatic neoplasms arising in the chest-wall (2 cases). No rejection was reported nor episodes of flail chest or respiratory disorders. No major complications occurred in patients who underwent postoperative radiotherapy; only 1 case of persistent seroma was observed. Followup ranges from 3 to 37 months. In no case was a local recurrence of tumor observed. Cosmetic results were considered from acceptable to good in all patients. In every case a total control of pain symptoms was achieved. There were 6 deaths at a mean interval of 22 months from operation (4 lung cancers, 1 breast cancer, 1 osteosarcoma), all due to metastatic spread of the disease.
自1987年1月起，在连续进行的56例胸壁癌切除术病例中，有14例（10例使用硅橡胶片，4例使用戈尔特斯软组织补片）采用假体植入修复胸壁缺损。胸壁切除的指征包括：T3期原发性肺癌（7例）、乳腺癌手术后局部复发（5例）、胸壁原发性和转移性肿瘤（2例）。未报告排斥反应，也未出现连枷胸或呼吸紊乱情况。接受术后放疗的患者未发生重大并发症；仅观察到1例持续性血清肿。随访时间为3至37个月。所有病例均未观察到肿瘤局部复发。所有患者的美容效果从可接受至良好。所有病例均实现了疼痛症状的完全控制。术后平均22个月有6例死亡（4例肺癌、1例乳腺癌、1例骨肉瘤），均因疾病转移扩散所致。
