Schreier K
MMW Munch Med Wochenschr. 1976 Dec 24;118(52-53):1695-1702.
In recent years it has been successfully demonstrated that, in relation to congenital metabolic abnormalities, every enzyme of the gastro-intestinal tract may be absent or inactive.. In serious diseases of the intestinal tract, secondary inactivation of numerous enzymes may result. In this comprehensive presentation the pathology of the disaccharidases, the peptidases and lypolysis is described, the physiology being gone into briefly in each case. Furthermore, all known disturbances of absorption of sugar, aminoacids and fats are briefly dealt with. Finally, congenital chloridorrhea is described.
近年来,已经成功证明,就先天性代谢异常而言,胃肠道的每种酶都可能缺失或无活性。在肠道的严重疾病中,可能会导致多种酶的继发性失活。在本综述中,描述了双糖酶、肽酶和脂肪分解的病理学,每种情况都简要介绍了其生理学。此外,还简要讨论了所有已知的糖、氨基酸和脂肪吸收障碍。最后,描述了先天性氯腹泻。