Cheah P L, Looi L M, Sivanesaratnam V
Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Malays J Pathol. 1993 Jun;15(1):59-63.
A review of gestational trophoblastic disease diagnosed at the Department of Pathology, University Hospital, Kuala Lumpur from January 1989 to December 1990 using established histological criteria showed 25 complete hydatidiform moles (CHM), 11 partial hydatidiform moles (PHM), 1 invasive mole and 2 choriocarcinoma. The ages of the patients with CHM ranged from 21 to 43 years (mean = 28.5 years) and PHM 20 to 33 years (mean = 27.5 years). The invasive mole occurred in a 42-year-old Malay woman. The two patients with choriocarcinoma were both Chinese and 41 and 46-years old respectively. During the same period, 1,062 non-molar abortions and 13,115 births, inclusive of livebirths and stillbirths were recorded at the University Hospital. The incidence rate of hydatidiform moles was thus estimated to be 1:384 pregnancies. PHM constituted 30% of all molar pregnancies. Hydatidiform moles occurred among the Malays, Chinese and Indians at the rate of 2.43, 2.66 and 3.29 per 1,000 pregnancies respectively. It appears that hydatidiform molar pregnancy has the highest prevalence among the Indians, a finding similar to an earlier Singapore study.
对1989年1月至1990年12月在吉隆坡大学医院病理科根据既定组织学标准诊断的妊娠滋养细胞疾病进行回顾，结果显示有25例完全性葡萄胎（CHM）、11例部分性葡萄胎（PHM）、1例侵蚀性葡萄胎和2例绒毛膜癌。CHM患者年龄在21至43岁之间（平均 = 28.5岁），PHM患者年龄在20至33岁之间（平均 = 27.5岁）。侵蚀性葡萄胎发生在一名42岁的马来女性身上。两名绒毛膜癌患者均为中国人，年龄分别为41岁和46岁。同一时期，该大学医院记录了1062例非葡萄胎流产以及13115例分娩，包括活产和死产。因此，葡萄胎的发病率估计为每384次妊娠中有1例。PHM占所有葡萄胎妊娠的30%。葡萄胎在马来人、中国人和印度人中的发生率分别为每1000次妊娠2.43例、2.66例和3.29例。看来葡萄胎妊娠在印度人中的患病率最高，这一发现与新加坡早期的一项研究相似。
